Chemical Biology/ Chemical Genetics/ Chemical Genomics: Importance of Chemical Library
نویسندگان
چکیده
منابع مشابه
Chemical Biology/ Chemical Genetics/ Chemical Genomics: Importance of Chemical Library
A new field of science, chemical biology/ chemical genetics/ chemical genomics (cb/cg/cg) has emerged since the late 1990's, especially in the United States. The NIH Roadmap agenda, Molecular Libraries Screening Center Network (MLSCN), became a drive force to push cb/cg/cg forward. Cb/cg/cg studies consist of three methodologies, chemical libraries with small molecules, high-throughput screenin...
متن کاملChemical genetics to chemical genomics: small molecules offer big insights.
Chemical genetics is the study of biological systems using small molecule ('chemical') intervention, instead of only genetic intervention. Cell-permeable and selective small molecules can be used to perturb protein function rapidly, reversibly and conditionally with temporal and quantitative control in any biological system. This tutorial review has been written to introduce this emerging field...
متن کاملChemical genomics.
Chemical genomics. By S. Jaroch and H. Weinmann (Editors). Ernst Schering Research Foundation Workshop 58. Pp. VII+173. Berlin: Springer-Verlag, 2006. Price 64.15 Euro. ISBN 103 54
متن کاملChemical Genomics
The book’s first few chapters deal with an introduction to bioinformatics, sequence analysis, and the diverse Internet resources currently available. The following chapters guide the reader through the databases of BLAST: BLASTN, BLASTP, BLASTX, and TBLASTN. Each chapter is set up to conduct you through a particular example query (or two), and is supplemented with specific screen shots from the...
متن کاملChemical genetics: tailoring tools for cell biology.
Chemical genetics is a research approach that uses small molecules as probes to study protein functions in cells or whole organisms. Here, I review the parallels between classical genetic and chemical-genetic approaches and discuss the merits of small molecules to dissect dynamic cellular processes. I then consider the pros and cons of different screening approaches and specify strategies aimed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chem-Bio Informatics Journal
سال: 2007
ISSN: 1347-0442,1347-6297
DOI: 10.1273/cbij.7.49